Ark is a novel simulation platform for biomanufacturing, accelerating the development and production of new cell culture and fermentation products for leading biotech, pharma, and climate companies. Our team is made up of world-renowned experts in bioprocessing, biomanufacturing, simulation and automation, all working together to create the first platform capable of accurately modeling and optimizing the production of modern cell culture and fermentation products. Our simulation engine, or “virtual bioreactor,” frees Ark customers from the limits of the wet-lab, allowing them to run unlimited experiments, save months of expensive trial-and-error, and get more drugs to clinical trials, faster. Fully optimized bioprocessing promises to save customers $100Ms in scale-up and biomanufacturing costs, helping to reverse the trend of skyrocketing development timelines and costs. About the role We are seeking a Senior Simulation Software Engineer to lead the development of our simulation engine, working closely with our team of PhD-level bioprocess modelers and fullstack software engineers. Ideal candidates for this role will quickly ramp up to own the full complexity of ODE / PDE features, and ensure that simulations are accurate, performant, and scalable. You will lead the development of both mechanistic models and ML features and use expert judgment in the selection of the right approach for each problem. This role is critical to ensuring that our advanced bioprocess models are both robust and efficient. Note: the level and corresponding title for this position will be determined based on the candidate's experience and qualifications. Key responsibilites

Own the simulation engine powering the Ark platform
Collaborate closely with world-class (PhD+) modeling scientists to design and productize mechanistic and ML models into optimized software implementations
Develop, maintain, and enhance high-performance code that drives our virtual bioreactor simulations
Integrate complex bioprocess models into Ark’s bioprocess copilot, focusing on flexibility, scalability, and performance
Build continuous testing and validation of software to ensure model accuracy and reliability in various bioprocess scenarios
Act as a bridge between the modeling and software engineering teams, facilitating clear communication and effective collaboration

Requirements

Experience developing simulations of complex systems using technologies such as numpy, scipy, or scikit learn
Proven experience in developing production software, preferably in the context of an early-stage startup.
Experience with scientific computing and algorithm development
Fluent in python
Strong problem-solving skills and the ability to work in a collaborative, fast-paced environment
Excellent communication skills to effectively convey technical concepts between multidisciplinary teams

Preferred Experience:

Masters or PhD-level experience with simulation of dynamic systems using ODEs/PDEs
Experience with ML, mechanistic, and hybrid modeling, and a nuanced appreciation for the pros and cons of each
Experience with compiled languages (C++, Rust) and/or JIT-compiled python (e.g., JAX, numba)

Position

Full-time, exempt
Cambridge, MA (in-person required)
Benefits include health, dental, and vision coverage, holiday and vacation time, 401k matching, stock options, and opportunity for career advancement as the company grows

Ark Biotech is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability status.

Software Engineering jobs in Needham

Senior Simulation Software Engineer